NPIPA9

Across TCGA patient cohorts, NPIPA9 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NPIPA9-associated genes across cancer lineages are RNA5SP516, RNU6-213P, and MIR181C. Each is linked with NPIPA9 in more than 1 cancer types. Because this analysis shows association rather than direction, both NPIPA9-to-partner and partner-to-NPIPA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP516 grouped by NPIPA9-low versus NPIPA9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPIPA9→partner) and Y-score (partner→NPIPA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP516 →	+0.637	+4.352	<.001	.008	3	1
UCEC	RNU6-213P →	+0.874	+4.838	<.001	<.001	3	1
UCEC	MIR181C →	+0.952	+5.048	<.001	<.001	3	1
UCEC	MIR550A1 →	+0.587	+4.184	.001	.003	3	1
UCEC	RNU6-588P →	+0.523	+4.302	<.001	.002	3	1
UCEC	RBISP1 →	+0.275	+3.719	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

RNA5SP516 by NPIPA9 expression — UCEC

Explore this box plot interactively →