NPIPA8

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NPIPA8 mutation is significantly associated with the RNA expression of many other genes, with 49 significant associations in total. CESC shows the largest number of these associations.

The most reproducible NPIPA8-associated genes across cancer lineages are NPVF, NPBWR2, and HMGB4. Each is linked with NPIPA8 in more than 1 cancer types. Because this analysis shows association rather than direction, both NPIPA8-to-partner and partner-to-NPIPA8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPIPA8→partner) and Y-score (partner→NPIPA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCNPVF →+0.124+5.812<.001.00331
CESCNPBWR2 →+0.056+5.010<.001.00931
CESCHMGB4 →+0.018+5.306<.001.00631
CESCRNA5SP447 →+0.349+5.201.004.00731
CESCRNU6-128P →+0.398+5.306<.001.00631
CESCTRIM51GP →+0.711+5.201<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

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