Across TCGA patient cohorts, NPIPA5 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NPIPA5-associated genes across cancer lineages are IGKV2OR2-7D, IGKV2OR2-2, and ATF4P2. Each is linked with NPIPA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both NPIPA5-to-partner and partner-to-NPIPA5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPIPA5→partner) and Y-score (partner→NPIPA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGKV2OR2-7D →	+0.133	+4.771	.003	.006	3	1
UCEC	IGKV2OR2-2 →	+0.388	+5.344	<.001	.001	3	1
UCEC	ATF4P2 →	+0.110	+5.184	<.001	.001	3	1
UCEC	MIR6075 →	+0.664	+5.223	<.001	.001	3	1
UCEC	RN7SL301P →	+0.396	+4.809	<.001	.003	3	1
UCEC	PANDAR →	+0.051	+4.840	.007	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

NPIPA5 survival (RNA) · tumor vs normal (RNA) · all NPIPA5 data types