NPHS2

Across TCGA patient cohorts, NPHS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,230 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NPHS2-associated GO terms across cancer lineages are Endosomal transport, Glycerolipid biosynthetic process, and Regulation of chromatin organization. Each is linked with NPHS2 in more than 14 cancer types. Because this analysis shows association rather than direction, both NPHS2-to-partner and partner-to-NPHS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by NPHS2-low versus NPHS2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPHS2→partner) and Y-score (partner→NPHS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Endosomal transport →	+0.066	+0.103	<.001	.002	3	13
STAD	Glycerolipid biosynthetic process →	+0.042	+0.097	<.001	<.001	3	13
ESCA	Regulation of chromatin organization →	+0.065	+0.115	<.001	.003	2	14
STAD	tRNA metabolic process →	+0.057	+0.111	<.001	.008	1	15
STAD	Regulation of double-strand break repair →	+0.053	+0.115	<.001	.003	2	13
STAD	Regulation of heterochromatin organization →	+0.055	+0.120	<.001	.001	1	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,230 associations by consensus.

Endosomal transport by NPHS2 expression — STAD

Explore this box plot interactively →