NPHP3

Across TCGA cell cohorts, NPHP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,568 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NPHP3-associated GO terms across cancer lineages are Determination of pancreatic left/right asymmetry, Retrograde transport, endosome to Golgi, and Cytosolic transport. Each is linked with NPHP3 in more than 18 cancer types. Because this analysis shows association rather than direction, both NPHP3-to-partner and partner-to-NPHP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Determination of pancreatic left/right asymmetry grouped by NPHP3-low versus NPHP3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPHP3→partner) and Y-score (partner→NPHP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Determination of pancreatic left/right asymmetry →	+1.516	+1.079	<.001	<.001	3	19
BONE	Retrograde transport, endosome to Golgi →	+0.074	+1.066	.005	.001	3	18
BONE	Cytosolic transport →	+0.078	+0.954	.003	.003	3	17
LIVER	Determination of liver left/right asymmetry →	+1.280	+0.924	<.001	<.001	3	17
BLOOD_Leukemia	Vacuolar transport →	+0.039	+0.848	<.001	<.001	3	17
BONE	Endosomal transport →	+0.060	+1.005	.002	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,568 associations by consensus.

Determination of pancreatic left/right asymmetry by NPHP3 expression — OVARY

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