NPFFR2

Across TCGA cell cohorts, NPFFR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 840 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible NPFFR2-associated GO terms across cancer lineages are Cytoplasmic translation, Motile cilium assembly, and Protein folding. Each is linked with NPFFR2 in more than 5 cancer types. Because this analysis shows association rather than direction, both NPFFR2-to-partner and partner-to-NPFFR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by NPFFR2-low versus NPFFR2-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPFFR2→partner) and Y-score (partner→NPFFR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Cytoplasmic translation →	+0.042	+0.734	.002	.008	3	6
CNS	Motile cilium assembly →	-0.029	-1.084	<.001	.001	3	6
LUNG_NSCLC_LUSC	Protein folding →	+0.067	+1.567	.002	.008	3	5
SKIN	Positive regulation of protein exit from endoplasmic reticulum →	+0.091	+0.413	<.001	.009	3	5
STOMACH	Establishment of protein localization to organelle →	+0.045	+1.993	<.001	.001	3	4
SOFT_TISSUE	Protein localization to cell periphery →	+0.039	+1.182	<.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 840 associations by consensus.

Cytoplasmic translation by NPFFR2 expression — CNS

Explore this box plot interactively →