Across TCGA patient cohorts, NPEPL1 mutation is significantly associated with the RNA expression of many other genes, with 2,837 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NPEPL1-associated genes across cancer lineages are KRTAP12-3, DGCR11, and SNRPGP7. Each is linked with NPEPL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NPEPL1-to-partner and partner-to-NPEPL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPEPL1→partner) and Y-score (partner→NPEPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	KRTAP12-3 →	+0.065	+4.984	<.001	.003	3	2
UCEC	DGCR11 →	+0.383	+2.815	<.001	<.001	3	2
STAD	SNRPGP7 →	+0.284	+3.565	<.001	.004	3	2
HNSC	MIR6795 →	+0.438	+7.954	<.001	.008	3	2
LIHC	MIR1226 →	+0.407	+6.169	<.001	<.001	3	2
UCEC	SNRPD3 →	+0.312	+2.345	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,837 associations by consensus.

Exploration

NPEPL1 survival (RNA) · tumor vs normal (RNA) · all NPEPL1 data types