Across TCGA patient cohorts, NPEPL1 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NPEPL1-associated genes across cancer lineages are ACC1, ARID1A, and TIGAR. Each is linked with NPEPL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NPEPL1-to-partner and partner-to-NPEPL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPEPL1→partner) and Y-score (partner→NPEPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC1 →	+0.269	+1.498	.024	.032	3	2
UCEC	ARID1A →	-0.123	-1.874	.043	.048	3	2
UCEC	TIGAR →	+0.117	+1.418	.020	.012	3	2
UCEC	ATM →	-0.429	-2.687	.004	.005	3	2
UCEC	beta-Catenin →	+0.349	+1.700	.036	.040	3	2
UCEC	c-Kit →	-0.186	-2.446	.015	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Exploration

NPEPL1 survival (RNA) · tumor vs normal (RNA) · all NPEPL1 data types