Across TCGA cell cohorts, NPEPL1 mutation is significantly associated with the RNA expression of many other genes, with 422 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NPEPL1-associated genes across cancer lineages are SEL1L2, REG1B, and MYH6. Each is linked with NPEPL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NPEPL1-to-partner and partner-to-NPEPL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPEPL1→partner) and Y-score (partner→NPEPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	SEL1L2 →	+0.022	+4.087	<.001	.009	3	1
PANCREAS	REG1B →	+0.025	+5.000	<.001	.006	3	1
PANCREAS	MYH6 →	+0.006	+5.000	<.001	.006	3	1
BLOOD_Leukemia	SYCN →	+0.035	+4.539	<.001	.007	3	1
LARGE_INTESTINE	EIF3L →	+0.573	+3.067	.001	.009	3	1
LARGE_INTESTINE	CHMP4B →	-0.576	-3.278	.007	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 422 associations by consensus.

Exploration

NPEPL1 survival (RNA) · tumor vs normal (RNA) · all NPEPL1 data types