NPBWR2

Across TCGA patient cohorts, NPBWR2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,091 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NPBWR2-associated genes across cancer lineages are PCMTD2, TMEM45A, and GPLD1. Each is linked with NPBWR2 in more than 5 cancer types. Because this analysis shows association rather than direction, both NPBWR2-to-partner and partner-to-NPBWR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NPBWR2 versus PCMTD2 in HNSC, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPBWR2→partner) and Y-score (partner→NPBWR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PCMTD2 →	-0.600	-0.545	<.001	<.001	3	6
CCRCC	TMEM45A →	+1.350	+0.772	<.001	<.001	3	6
GBM	GPLD1 →	-0.601	-0.409	<.001	<.001	3	5
LUAD	FHL2 →	+0.922	+0.722	<.001	<.001	3	5
UCEC	PDZK1P1 →	-0.523	-0.484	<.001	<.001	3	5
GBM	SARM1 →	-0.512	-0.363	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,091 associations by consensus.

NPBWR2 vs PCMTD2 — HNSC

Explore this scatter interactively →