Across TCGA patient cohorts, NPBWR1 mutation is significantly associated with the RNA expression of many other genes, with 569 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NPBWR1-associated genes across cancer lineages are MND1, NUSAP1, and CCNB2. Each is linked with NPBWR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NPBWR1-to-partner and partner-to-NPBWR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPBWR1→partner) and Y-score (partner→NPBWR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MND1 →	+0.736	+3.201	.005	.009	3	3
UCEC	NUSAP1 →	+0.745	+2.617	.006	.005	3	3
UCEC	CCNB2 →	+0.732	+3.201	.004	.009	3	3
UCEC	PBK →	+0.813	+2.233	.009	.006	3	3
UCEC	TAF9 →	+0.541	+3.700	.001	.001	3	2
READ	MIR2467 →	+0.612	+4.445	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 569 associations by consensus.

Exploration

NPBWR1 survival (RNA) · tumor vs normal (RNA) · all NPBWR1 data types