Across TCGA cell cohorts, NPBWR1 mutation is significantly associated with the RNA expression of many other genes, with 422 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NPBWR1-associated genes across cancer lineages are OR52B2, PRAMEF7, and CCDC134. Each is linked with NPBWR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NPBWR1-to-partner and partner-to-NPBWR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPBWR1→partner) and Y-score (partner→NPBWR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OR52B2 →	+0.024	+4.981	.004	.008	3	1
BLOOD_Leukemia	PRAMEF7 →	+0.017	+4.539	<.001	.007	3	1
LARGE_INTESTINE	CCDC134 →	+0.928	+3.131	<.001	.008	3	1
LARGE_INTESTINE	CENPM →	+0.693	+3.169	.006	.009	3	1
LARGE_INTESTINE	TNRC6B →	+0.862	+3.364	<.001	.002	3	1
LARGE_INTESTINE	USP14 →	+0.820	+3.389	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 422 associations by consensus.

Exploration

NPBWR1 survival (RNA) · tumor vs normal (RNA) · all NPBWR1 data types