NPAS2

Across TCGA cell cohorts, NPAS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,054 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NPAS2-associated GO terms across cancer lineages are Positive regulation of behavioral fear response, Positive regulation of fear response, and Regulation of behavioral fear response. Each is linked with NPAS2 in more than 14 cancer types. Because this analysis shows association rather than direction, both NPAS2-to-partner and partner-to-NPAS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of behavioral fear response grouped by NPAS2-low versus NPAS2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPAS2→partner) and Y-score (partner→NPAS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of behavioral fear response →	+1.497	+2.222	<.001	<.001	3	15
CNS	Positive regulation of fear response →	+1.026	+1.978	<.001	<.001	3	12
BREAST	Regulation of behavioral fear response →	+0.975	+2.028	<.001	<.001	3	11
BREAST	Regulation of fear response →	+0.698	+1.660	<.001	.002	3	10
STOMACH	Chromosomal 5-methylcytosine DNA demethylation pathway →	-0.178	-1.565	<.001	<.001	3	8
SOFT_TISSUE	Negative regulation of cell-cell adhesion →	+0.078	+2.247	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,054 associations by consensus.

Positive regulation of behavioral fear response by NPAS2 expression — OVARY

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