NPAS1

Across TCGA patient cohorts, NPAS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,443 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NPAS1-associated proteins across cancer lineages are TAP2, UNC13D, and PAFAH1B3. Each is linked with NPAS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both NPAS1-to-partner and partner-to-NPAS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NPAS1 versus TAP2 in PDAC, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NPAS1→partner) and Y-score (partner→NPAS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TAP2 →	-0.693	-0.317	<.001	<.001	3	4
LSCC	UNC13D →	-0.377	-0.504	<.001	<.001	3	4
BRCA	PAFAH1B3 →	+0.428	+0.563	<.001	<.001	3	4
BRCA	NCF1 →	-0.585	-0.684	<.001	<.001	3	4
OV	PDIA5 →	-0.510	-0.472	.003	.008	3	3
OV	PPP5C →	+0.247	+0.451	.003	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,443 associations by consensus.

NPAS1 vs TAP2 — PDAC

Explore this scatter interactively →