Across TCGA pan-cancer cohorts, NPAP1P2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of NPAP1P2’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where NPAP1P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NPAP1P2 is over-expressed in tumor, although a few such as LUSC and KICH show the opposite, repressed pattern.

BRCA, LUSC, and UCEC are the cancer types where NPAP1P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NPAP1P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	II,III,IV	+0.012	.007	4	view →
LUSC	Female	II,III,IV	−0.048	.004	2	view →
UCEC	All	II,III,IV	+0.040	.039	2	view →
KICH	All	II,III,IV	−0.023	.032	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: NPAP1P2 RNA expression & survival · all NPAP1P2 data types