Across TCGA patient cohorts, NPAP1 mutation is significantly associated with the total protein of many other genes, with 127 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NPAP1-associated genes across cancer lineages are ASNS, Cyclin-B1, and FoxM1. Each is linked with NPAP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both NPAP1-to-partner and partner-to-NPAP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPAP1→partner) and Y-score (partner→NPAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ASNS →	+0.341	+1.137	.003	.007	3	6
LUAD	Cyclin-B1 →	+0.581	+1.428	<.001	<.001	3	5
LUAD	FoxM1 →	+0.239	+3.281	<.001	<.001	3	4
LUAD	p21 →	+0.232	+1.137	.009	.007	3	4
LUAD	p38-MAPK →	-0.117	-2.180	.003	<.001	3	4
UCEC	PCNA →	+0.166	+1.306	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 127 associations by consensus.

Exploration

NPAP1 survival (RNA) · tumor vs normal (RNA) · all NPAP1 data types