NOXRED1

Across TCGA cell cohorts, NOXRED1 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NOXRED1-associated genes across cancer lineages are DEFB129, MROH2B, and OPN4. Each is linked with NOXRED1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOXRED1-to-partner and partner-to-NOXRED1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB129 grouped by NOXRED1-low versus NOXRED1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOXRED1→partner) and Y-score (partner→NOXRED1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	DEFB129 →	+0.032	+5.247	<.001	.001	3	1
BLOOD_Lymphoma	MROH2B →	+0.063	+4.643	<.001	.005	3	1
LARGE_INTESTINE	OPN4 →	+0.013	+4.930	.007	.001	3	1
LARGE_INTESTINE	FTHL17 →	+0.060	+4.415	<.001	.007	3	1
LARGE_INTESTINE	MSGN1 →	+0.089	+4.930	<.001	.001	3	1
LARGE_INTESTINE	TAFA1 →	+0.418	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

DEFB129 by NOXRED1 expression — BLOOD_Lymphoma

Explore this box plot interactively →