Across TCGA patient cohorts, NOXO1 protein abundance is significantly associated with the RNA expression of many other genes, with 113 significant associations in total. COAD shows the largest number of these associations.

The most reproducible NOXO1-associated genes across cancer lineages are SLC32A1, SLC11A2, and PRDM13. Each is linked with NOXO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOXO1-to-partner and partner-to-NOXO1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOXO1→partner) and Y-score (partner→NOXO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SLC32A1 →	+0.063	+1.516	.002	<.001	3	1
COAD	SLC11A2 →	+0.727	+1.300	.005	.005	3	1
COAD	PRDM13 →	+0.391	+1.394	.004	.002	3	1
COAD	SMAP1 →	+0.463	+1.481	.001	<.001	3	1
COAD	SEMA5A →	+1.154	+1.246	.003	.004	3	1
COAD	TMEM74B →	-1.351	-1.160	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 113 associations by consensus.

Exploration

NOXO1 survival (RNA) · tumor vs normal (RNA) · all NOXO1 data types