NOXO1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NOXO1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NOXO1-associated genes across cancer lineages are UNCX, NKX2-6, and FAM24A. Each is linked with NOXO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOXO1-to-partner and partner-to-NOXO1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOXO1→partner) and Y-score (partner→NOXO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaUNCX →+0.006+4.807<.001.00631
BLOOD_LeukemiaNKX2-6 →+0.591+5.201<.001.00631
BLOOD_LeukemiaFAM24A →+0.085+5.969<.001.00131
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

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