Across TCGA pan-cancer cohorts, NOXA1 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated NOXA1 data layer compared with 23 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher NOXA1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated NOXA1 expression acts as an unfavorable survival marker.

KICH are the cancer types where NOXA1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	All	0.162	0.862	.014	10	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: NOXA1 tumor-vs-normal RNA expression · all NOXA1 data types