Across TCGA patient cohorts, NOXA1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,435 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NOXA1-associated genes across cancer lineages are SEPTIN3, FAM83E, and GARS1. Each is linked with NOXA1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NOXA1-to-partner and partner-to-NOXA1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOXA1→partner) and Y-score (partner→NOXA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEPTIN3 →	-0.953	-0.409	<.001	<.001	3	3
BRCA	FAM83E →	+1.793	+0.487	<.001	<.001	3	3
LSCC	GARS1 →	-0.673	-0.607	.002	.005	3	3
BRCA	BBOF1 →	+1.068	+0.647	<.001	<.001	3	3
BRCA	NXNL2 →	+1.786	+0.610	<.001	<.001	3	3
LSCC	ALDH1L2 →	-0.850	-0.777	.004	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,435 associations by consensus.

Exploration

NOXA1 survival (RNA) · tumor vs normal (RNA) · all NOXA1 data types