NOX5

Across TCGA patient cohorts, NOX5 protein abundance is significantly associated with the RNA expression of many other genes, with 263 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible NOX5-associated genes across cancer lineages are OAZ1, HBP1, and CCNI. Each is linked with NOX5 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOX5-to-partner and partner-to-NOX5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NOX5 versus OAZ1 in CCRCC, with a Pearson correlation of -0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOX5→partner) and Y-score (partner→NOX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	OAZ1 →	-0.568	-0.276	.009	.005	3	1
CCRCC	HBP1 →	+0.322	+0.355	.004	.009	3	1
CCRCC	CCNI →	+0.641	+0.286	<.001	.003	3	1
CCRCC	DENND1A →	+0.441	+0.276	.003	.005	3	1
CCRCC	TGFBI →	-2.885	-0.399	<.001	.003	3	1
CCRCC	CAT →	+0.946	+0.473	.008	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 263 associations by consensus.

NOX5 vs OAZ1 — CCRCC

Explore this scatter interactively →