NOX5

Across TCGA cell cohorts, NOX5 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,823 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NOX5-associated GO terms across cancer lineages are Regulation of myoblast fusion, Regulation of intrinsic apoptotic signaling pathway, and Positive regulation of dendrite extension. Each is linked with NOX5 in more than 8 cancer types. Because this analysis shows association rather than direction, both NOX5-to-partner and partner-to-NOX5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by NOX5-low versus NOX5-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NOX5→partner) and Y-score (partner→NOX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of myoblast fusion →	+0.050	+0.033	<.001	.003	3	9
BLOOD_Lymphoma	Regulation of intrinsic apoptotic signaling pathway →	+0.049	+0.596	<.001	.004	3	8
LUNG_SCLC	Positive regulation of dendrite extension →	-0.103	-0.506	<.001	<.001	3	7
KIDNEY	Mitochondrial electron transport, cytochrome c to oxygen →	+0.076	+0.253	.006	.002	3	7
LUNG_NSCLC_LUAD	Regulation of protein localization to mitochondrion →	+0.059	+0.718	<.001	.003	3	7
LARGE_INTESTINE	Viral process →	+0.035	+0.091	.003	.008	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,823 associations by consensus.

Regulation of myoblast fusion by NOX5 expression — BLOOD_Leukemia

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