NOX4

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NOX4 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,076 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NOX4-associated proteins across cancer lineages are P3H1, PDLIM7, and CRTAP. Each is linked with NOX4 in more than 8 cancer types. Because this analysis shows association rather than direction, both NOX4-to-partner and partner-to-NOX4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NOX4 versus P3H1 in GBM, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NOX4→partner) and Y-score (partner→NOX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMP3H1 →+0.750+0.495<.001.00139
BRCAPDLIM7 →+0.747+1.275<.001<.00139
BRCACRTAP →+0.749+1.061<.001<.00139
BRCAFILIP1L →+0.577+1.092<.001<.00139
PDACFILIP1L_S1041 →+0.967+0.581<.001<.00139
BRCACALD1 →+0.801+1.208<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,076 associations by consensus.

NOX4 vs P3H1 — GBM

Per-sample scatter of NOX4 vs P3H1 in GBM (Pearson r = 0.37).

Explore this scatter interactively →

Exploration