NOVA2

Across TCGA cell cohorts, NOVA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,290 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NOVA2-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Positive regulation of sodium ion transmembrane transport, and Locomotory exploration behavior. Each is linked with NOVA2 in more than 7 cancer types. Because this analysis shows association rather than direction, both NOVA2-to-partner and partner-to-NOVA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by NOVA2-low versus NOVA2-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NOVA2→partner) and Y-score (partner→NOVA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Negative regulation of myoblast fusion →	+0.059	+0.616	<.001	.007	3	8
OVARY	Positive regulation of sodium ion transmembrane transport →	-0.304	-0.958	<.001	<.001	3	7
OESOPHAGUS	Locomotory exploration behavior →	+0.244	+0.583	<.001	.001	3	7
SKIN	Phospholipase C-activating G protein-coupled receptor signaling pathway →	-0.031	-0.416	.001	.004	3	7
CNS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.075	+0.790	<.001	.002	3	7
SKIN	Electron transport chain →	+0.065	+0.788	.002	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,290 associations by consensus.

Negative regulation of myoblast fusion by NOVA2 expression — CNS

Explore this box plot interactively →