NOTO

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NOTO mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. CNS shows the largest number of these associations.

The most reproducible NOTO-associated genes across cancer lineages are DEFB133. Each is linked with NOTO in more than 1 cancer types. Because this analysis shows association rather than direction, both NOTO-to-partner and partner-to-NOTO results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOTO→partner) and Y-score (partner→NOTO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CNSDEFB133 →+0.035+5.357<.001.00131
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Exploration