NOTCH2NLR

Across TCGA patient cohorts, NOTCH2NLR RNA expression is significantly associated with the protein abundance of many other proteins, with 5,025 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible NOTCH2NLR-associated proteins across cancer lineages are NUP98_S839, SIPA1L3_S100, and CCDC124_S141. Each is linked with NOTCH2NLR in more than 2 cancer types. Because this analysis shows association rather than direction, both NOTCH2NLR-to-partner and partner-to-NOTCH2NLR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NOTCH2NLR versus NUP98_S839 in LUAD, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NOTCH2NLR→partner) and Y-score (partner→NOTCH2NLR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NUP98_S839 →	-0.599	-0.569	<.001	<.001	3	3
GBM	SIPA1L3_S100 →	+0.424	+0.488	<.001	.001	3	2
HNSC	CCDC124_S141 →	+0.311	+0.501	.007	.005	3	2
LUAD	CCT2 →	-0.190	-0.577	.002	<.001	3	2
LUAD	GPT2 →	-0.686	-0.593	.003	<.001	3	2
HNSC	HDAC5 →	+0.257	+0.505	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,025 associations by consensus.

NOTCH2NLR vs NUP98_S839 — LUAD

Explore this scatter interactively →