NOSIP

Across TCGA patient cohorts, NOSIP RNA expression is significantly associated with the protein abundance of many other proteins, with 7,458 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible NOSIP-associated proteins across cancer lineages are PRMT1, PRR12, and PNKP. Each is linked with NOSIP in more than 4 cancer types. Because this analysis shows association rather than direction, both NOSIP-to-partner and partner-to-NOSIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NOSIP versus PRMT1 in BRCA, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NOSIP→partner) and Y-score (partner→NOSIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PRMT1 →	+0.380	+0.732	<.001	<.001	3	5
GBM	PRR12 →	+0.325	+0.344	<.001	<.001	3	5
OV	PNKP →	+0.334	+0.560	.001	.003	3	5
GBM	PTOV1_S36 →	+0.377	+0.323	<.001	<.001	3	4
CCRCC	RRBP1 →	-0.303	-0.257	.003	<.001	3	4
HNSC	SEC31A →	-0.234	-0.831	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,458 associations by consensus.

NOSIP vs PRMT1 — BRCA

Explore this scatter interactively →