Across TCGA pan-cancer cohorts, NOS2P2 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of NOS2P2’s most consistent transcriptional readouts.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where NOS2P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NOS2P2 is over-expressed in tumor.
UCEC, BLCA, and HNSC are the cancer types where NOS2P2 tumor–normal differential expression is most reproducible.