NOS1

Across TCGA patient cohorts, NOS1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,265 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NOS1-associated genes across cancer lineages are NRSN1, CHADL, and NGB. Each is linked with NOS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NOS1-to-partner and partner-to-NOS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NOS1 versus NRSN1 in GBM, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOS1→partner) and Y-score (partner→NOS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NRSN1 →	+1.047	+0.554	<.001	<.001	3	3
GBM	CHADL →	+1.241	+0.522	<.001	<.001	3	3
GBM	NGB →	+1.223	+0.843	<.001	<.001	3	3
GBM	SNCG →	+1.454	+0.746	<.001	<.001	3	3
OV	SLIT3 →	+1.678	+1.231	<.001	.008	3	3
COAD	CCDC69 →	+0.785	+0.576	.003	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,265 associations by consensus.

NOS1 vs NRSN1 — GBM

Explore this scatter interactively →