NOP58

Across TCGA cell cohorts, NOP58 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,325 significant associations in total. CNS shows the largest number of these associations.

The most reproducible NOP58-associated GO terms across cancer lineages are Maturation of SSU-rRNA, Replication fork processing, and Ribosomal small subunit biogenesis. Each is linked with NOP58 in more than 19 cancer types. Because this analysis shows association rather than direction, both NOP58-to-partner and partner-to-NOP58 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of SSU-rRNA grouped by NOP58-low versus NOP58-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NOP58→partner) and Y-score (partner→NOP58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Maturation of SSU-rRNA →	+0.127	+0.933	<.001	.001	3	20
BONE	Replication fork processing →	+0.152	+1.186	.003	<.001	3	20
BONE	Ribosomal small subunit biogenesis →	+0.120	+0.910	<.001	.001	3	20
BONE	DNA-templated DNA replication maintenance of fidelity →	+0.152	+1.096	.002	.002	3	20
BONE	Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.167	+0.986	<.001	<.001	3	20
BONE	DNA replication initiation →	+0.218	+1.061	.001	.004	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,325 associations by consensus.

Maturation of SSU-rRNA by NOP58 expression — BONE

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