Across TCGA pan-cancer cohorts, NOP56P2 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of NOP56P2’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where NOP56P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NOP56P2 is over-expressed in tumor.
KIRC are the cancer types where NOP56P2 tumor–normal differential expression is most reproducible.