NOP56

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NOP56 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,178 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NOP56-associated proteins across cancer lineages are TRMT6, PCNA, and ESF1. Each is linked with NOP56 in more than 9 cancer types. Because this analysis shows association rather than direction, both NOP56-to-partner and partner-to-NOP56 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NOP56 versus TRMT6 in LSCC, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NOP56→partner) and Y-score (partner→NOP56) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCTRMT6 →+0.476+0.673<.001<.001310
COADPCNA →+0.690+0.887<.001<.00139
LSCCESF1 →+0.488+0.753<.001<.00139
BRCAUTP4 →+0.450+0.590<.001<.00138
PDACCHAF1B →+0.585+0.604<.001.00138
LSCCESF1_S153 →+0.903+0.715<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 21,178 associations by consensus.

NOP56 vs TRMT6 — LSCC

Per-sample scatter of NOP56 vs TRMT6 in LSCC (Pearson r = 0.64).

Explore this scatter interactively →

Exploration