NOP56

Across TCGA cell cohorts, NOP56 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,519 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NOP56-associated GO terms across cancer lineages are 'de novo' IMP biosynthetic process, Nucleolar large rRNA transcription by RNA polymerase I, and 'de novo' AMP biosynthetic process. Each is linked with NOP56 in more than 18 cancer types. Because this analysis shows association rather than direction, both NOP56-to-partner and partner-to-NOP56 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 'de novo' IMP biosynthetic process grouped by NOP56-low versus NOP56-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NOP56→partner) and Y-score (partner→NOP56) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	'de novo' IMP biosynthetic process →	+0.242	+1.787	<.001	<.001	3	19
BONE	Nucleolar large rRNA transcription by RNA polymerase I →	+0.170	+1.644	<.001	<.001	3	18
BONE	'de novo' AMP biosynthetic process →	+0.235	+1.645	<.001	<.001	3	18
BONE	DNA replication proofreading →	+0.210	+1.215	<.001	.001	3	18
BONE	Maturation of 5.8S rRNA →	+0.181	+1.667	<.001	<.001	3	18
BONE	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.142	+1.426	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,519 associations by consensus.

'de novo' IMP biosynthetic process by NOP56 expression — BONE

Explore this box plot interactively →