NOP53

Across TCGA cell cohorts, NOP53 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,850 significant associations in total. CNS shows the largest number of these associations.

The most reproducible NOP53-associated GO terms across cancer lineages are Hydrogen sulfide metabolic process, Short-chain fatty acid catabolic process, and Regulation of protection from non-homologous end joining at telomere. Each is linked with NOP53 in more than 9 cancer types. Because this analysis shows association rather than direction, both NOP53-to-partner and partner-to-NOP53 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hydrogen sulfide metabolic process grouped by NOP53-low versus NOP53-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NOP53→partner) and Y-score (partner→NOP53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Hydrogen sulfide metabolic process →	+0.181	+0.776	.003	.004	3	10
STOMACH	Short-chain fatty acid catabolic process →	+0.147	+0.884	<.001	.003	3	8
STOMACH	Regulation of protection from non-homologous end joining at telomere →	+0.177	+1.023	<.001	.005	3	8
STOMACH	Negative regulation of protection from non-homologous end joining at telomere →	+0.177	+1.023	<.001	.005	3	8
STOMACH	Telomeric DNA-containing double minutes formation →	+0.177	+1.023	<.001	.005	3	8
SOFT_TISSUE	Peptidyl-glutamate ADP-deribosylation →	+0.159	+0.506	.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,850 associations by consensus.

Hydrogen sulfide metabolic process by NOP53 expression — PANCREAS

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