NOP2

Across TCGA patient cohorts, NOP2 protein abundance is significantly associated with the RNA expression of many other genes, with 21,418 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NOP2-associated genes across cancer lineages are LMOD1, CBX7, and GAPDH. Each is linked with NOP2 in more than 9 cancer types. Because this analysis shows association rather than direction, both NOP2-to-partner and partner-to-NOP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NOP2 versus LMOD1 in COAD, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOP2→partner) and Y-score (partner→NOP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LMOD1 →	-1.237	-0.229	<.001	<.001	3	10
OV	CBX7 →	-0.749	-0.409	.002	.001	3	9
HNSC	GAPDH →	+1.057	+0.212	.001	.003	3	9
OV	APBB1 →	-1.085	-0.540	<.001	<.001	3	9
CCRCC	NEGR1 →	-0.837	-0.271	.008	.003	2	10
BRCA	RAD51AP1 →	+0.974	+0.791	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,418 associations by consensus.

NOP2 vs LMOD1 — COAD

Explore this scatter interactively →