NOP2

Across TCGA patient cohorts, NOP2 mutation is significantly associated with the RNA expression of many other genes, with 1,303 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOP2-associated genes across cancer lineages are CORO1C, TAF13, and ISCA1P3. Each is linked with NOP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NOP2-to-partner and partner-to-NOP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CORO1C grouped by NOP2-low versus NOP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOP2→partner) and Y-score (partner→NOP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CORO1C →	+0.523	+2.254	.002	.005	3	3
UCEC	TAF13 →	+0.637	+3.593	.001	.001	3	3
BLCA	ISCA1P3 →	+0.081	+3.411	<.001	.005	3	3
SKCM	STAG3L4 →	+0.694	+3.328	.004	.005	3	2
LIHC	MIR2114 →	+0.317	+7.495	<.001	<.001	3	2
COAD	KDSR →	+0.704	+3.210	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,303 associations by consensus.

CORO1C by NOP2 expression — UCEC

Explore this box plot interactively →