NOP14

Across TCGA cell cohorts, NOP14 mutation is significantly associated with the drug of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NOP14-associated genes across cancer lineages are BDILV000379a, TAK-715, and CP724714. Each is linked with NOP14 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOP14-to-partner and partner-to-NOP14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BDILV000379a grouped by NOP14-low versus NOP14-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOP14→partner) and Y-score (partner→NOP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BDILV000379a →	+0.293	+2.678	.036	.037	3	1
LARGE_INTESTINE	TAK-715 →	+0.387	+2.722	.042	.023	3	1
LARGE_INTESTINE	CP724714 →	+0.338	+2.807	.026	.032	3	1
LARGE_INTESTINE	CI-1033 →	+0.715	+2.691	.008	.032	3	1
LARGE_INTESTINE	TWS119 →	+0.492	+2.807	.020	.032	3	1
LARGE_INTESTINE	Pilaralisib →	+0.288	+2.807	.039	.032	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

BDILV000379a by NOP14 expression — LARGE_INTESTINE

Explore this box plot interactively →