NOP14-AS1

Across TCGA pan-cancer cohorts, NOP14-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated NOP14-AS1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher NOP14-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated NOP14-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and ESCA show a favorable association.

UCS, ESCA, and KIRP are the cancer types where NOP14-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Quartile	II,III,IV	0.771	0.210	<.001	76	view →
ESCA	DFS	Quartile	All	0.857	0.118	.002	33	view →
KIRP	OS	Quartile	All	0.890	0.608	.004	31	view →
CHOL	OS	Tertile	All	0.881	0.468	.005	30	view →
BRCA	OS	Median	III,IV	0.888	0.767	.007	29	view →
LUSC	DFS	Quartile	II,III,IV	0.173	0.713	.001	26	view →
COAD	DFS	Median	II,III,IV	0.369	0.675	.002	19	view →
ACC	OS	Median	II,III,IV	0.714	0.949	.021	13	view →
GBM	OS	Median	All	0.225	0.308	.021	12	view →
BLCA	DFS	Tertile	IV	0.260	0.558	.019	12	view →
THCA	DFS	Median	All	0.884	0.774	.015	11	view →
SKCM	DFS	Median	II,III,IV	0.625	0.784	.012	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

NOP14-AS1–UCS (OS)

Open the UCS breakdown →