NOMO3

Across TCGA cell cohorts, NOMO3 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible NOMO3-associated genes across cancer lineages are PRY, PRY2, and OR1L3. Each is linked with NOMO3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOMO3-to-partner and partner-to-NOMO3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRY grouped by NOMO3-low versus NOMO3-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOMO3→partner) and Y-score (partner→NOMO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PRY →	+0.023	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	PRY2 →	+0.023	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR1L3 →	+0.028	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	SPINK8 →	+0.591	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

PRY by NOMO3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →