Across TCGA patient cohorts, NOMO2 mutation is significantly associated with the RNA expression of many other genes, with 424 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOMO2-associated genes across cancer lineages are SMG9, DOHH, and POLD1. Each is linked with NOMO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOMO2-to-partner and partner-to-NOMO2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOMO2→partner) and Y-score (partner→NOMO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SMG9 →	+0.535	+3.475	<.001	.002	3	2
UCEC	DOHH →	+0.600	+3.627	.001	.001	3	2
UCEC	POLD1 →	+0.858	+3.257	<.001	.008	3	2
SKCM	MIR133B →	+0.772	+4.186	<.001	.007	3	2
COAD	RN7SL835P →	+0.527	+5.283	<.001	.006	3	2
BRCA	S100A11P8 →	+0.109	+8.471	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 424 associations by consensus.

Exploration

NOMO2 survival (RNA) · tumor vs normal (RNA) · all NOMO2 data types