NOMO1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NOMO1 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated NOMO1 data layer compared with 25 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher NOMO1 Mutation is associated with better overall survival. In most high-consensus cancer types, elevated NOMO1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and BLCA show a favorable association.

UCEC, HNSC, and COAD are the cancer types where NOMO1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSMedianAll1.0000.647.00534view →
HNSCDFSMedianIII,IV0.1610.680.01624view →
COADOSMedianIII,IV0.0560.793<.00124view →
LUSCOSMedianAll0.3500.677.02912view →
BLCADFSMedianAll0.8470.327.0326view →
SKCMOSMedianII,III,IV0.5810.848.0025view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

NOMO1–UCEC (OS)

Kaplan–Meier survival curve for NOMO1 mutant vs wild-type samples in UCEC.

Open the UCEC breakdown →

Exploration