NOMO1

Across TCGA patient cohorts, NOMO1 mutation is significantly associated with the RNA expression of many other genes, with 3,439 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOMO1-associated genes across cancer lineages are OIP5, PSMD9, and CDK2AP1. Each is linked with NOMO1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NOMO1-to-partner and partner-to-NOMO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OIP5 grouped by NOMO1-low versus NOMO1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOMO1→partner) and Y-score (partner→NOMO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OIP5 →	+0.774	+2.021	<.001	<.001	3	3
UCEC	PSMD9 →	+0.316	+1.781	.004	.008	3	3
UCEC	CDK2AP1 →	+0.488	+2.202	.005	.001	3	3
UCEC	ICMT →	+0.496	+2.021	<.001	<.001	3	3
UCEC	RITA1 →	+0.446	+2.534	<.001	<.001	3	3
UCEC	KIF2C →	+0.558	+2.332	.009	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,439 associations by consensus.

OIP5 by NOMO1 expression — UCEC

Explore this box plot interactively →