NOMO1

Across TCGA cell cohorts, NOMO1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,608 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NOMO1-associated GO terms across cancer lineages are Multi-pass transmembrane protein insertion into ER membrane, Negative regulation of nodal signaling pathway, and Positive regulation of protein exit from endoplasmic reticulum. Each is linked with NOMO1 in more than 17 cancer types. Because this analysis shows association rather than direction, both NOMO1-to-partner and partner-to-NOMO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Multi-pass transmembrane protein insertion into ER membrane grouped by NOMO1-low versus NOMO1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NOMO1→partner) and Y-score (partner→NOMO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Multi-pass transmembrane protein insertion into ER membrane →	+0.172	+1.437	<.001	.001	3	18
CNS	Negative regulation of nodal signaling pathway →	+0.202	+0.869	<.001	<.001	3	17
SOFT_TISSUE	Positive regulation of protein exit from endoplasmic reticulum →	+0.116	+0.805	<.001	.003	3	14
BONE	Glycoprotein biosynthetic process →	+0.079	+1.397	<.001	<.001	3	14
BONE	Biological process involved in symbiotic interaction →	+0.081	+0.909	<.001	<.001	3	13
CNS	Viral process →	+0.084	+1.008	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,608 associations by consensus.

Multi-pass transmembrane protein insertion into ER membrane by NOMO1 expression — LIVER

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