NOLC1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NOLC1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,703 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NOLC1-associated genes across cancer lineages are TWNK, HELLS, and KIF11. Each is linked with NOLC1 in more than 7 cancer types. Because this analysis shows association rather than direction, both NOLC1-to-partner and partner-to-NOLC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NOLC1 versus TWNK in OV, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOLC1→partner) and Y-score (partner→NOLC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVTWNK →+0.748+0.580<.001<.00138
LSCCHELLS →+0.843+0.334<.001<.00138
BRCAKIF11 →+1.004+0.678<.001<.00138
BRCAMKI67 →+0.940+0.476<.001<.00138
UCECCDK1 →+0.871+0.362<.001<.00138
LSCCSNHG1 →+0.611+0.399<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,703 associations by consensus.

NOLC1 vs TWNK — OV

Per-sample scatter of NOLC1 vs TWNK in OV (Pearson r = 0.52).

Explore this scatter interactively →

Exploration