NOL9

Across TCGA patient cohorts, NOL9 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOL9-associated genes across cancer lineages are JNK2, EGFR_pY1068, and eIF4E. Each is linked with NOL9 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOL9-to-partner and partner-to-NOL9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK2 grouped by NOL9-low versus NOL9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOL9→partner) and Y-score (partner→NOL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.239	+2.834	.005	.034	3	2
UCEC	EGFR_pY1068 →	-0.249	-2.807	.023	.003	3	1
UCEC	eIF4E →	+0.188	+2.807	.041	.003	3	1
UCEC	A-Raf_pS299 →	-0.114	-2.321	.029	.034	3	1
UCEC	ERK2 →	+0.226	+2.115	.007	.019	3	1
UCEC	HER3 →	+0.422	+2.820	<.001	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

JNK2 by NOL9 expression — UCEC

Explore this box plot interactively →