Across TCGA patient cohorts, NOL8 mutation is significantly associated with the RNA expression of many other genes, with 2,967 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOL8-associated genes across cancer lineages are MIR3927, RNU6-222P, and RPS2P25. Each is linked with NOL8 in more than 2 cancer types. Because this analysis shows association rather than direction, both NOL8-to-partner and partner-to-NOL8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOL8→partner) and Y-score (partner→NOL8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR3927 →	+0.271	+4.912	<.001	.003	3	3
PAAD	RNU6-222P →	+0.651	+5.213	<.001	.006	3	3
HNSC	RPS2P25 →	+0.270	+3.804	<.001	.005	3	3
BRCA	SNORD30 →	+0.530	+3.343	<.001	.004	3	2
CESC	MIR5189 →	+0.208	+4.569	<.001	.005	3	2
BLCA	FAHD1 →	+0.517	+3.205	.003	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,967 associations by consensus.

Exploration

NOL8 survival (RNA) · tumor vs normal (RNA) · all NOL8 data types