Across TCGA cell cohorts, NOL8 mutation is significantly associated with the RNA expression of many other genes, with 336 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NOL8-associated genes across cancer lineages are CCR8, BHLHA9, and GOLGA6L6. Each is linked with NOL8 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOL8-to-partner and partner-to-NOL8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOL8→partner) and Y-score (partner→NOL8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CCR8 →	+0.022	+5.369	<.001	.004	3	1
SOFT_TISSUE	BHLHA9 →	+0.036	+5.977	<.001	.001	3	1
SOFT_TISSUE	GOLGA6L6 →	+0.013	+5.369	<.001	.004	3	1
OESOPHAGUS	HTR5A →	+0.006	+4.906	<.001	.006	3	1
BLOOD_Myeloma	GP2 →	+0.026	+4.807	<.001	.006	3	1
LUNG_NSCLC_LUSC	GAGE12J →	+0.266	+4.643	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 336 associations by consensus.

Exploration

NOL8 survival (RNA) · tumor vs normal (RNA) · all NOL8 data types