Across TCGA patient cohorts, NOL7 mutation is significantly associated with the RNA expression of many other genes, with 86 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOL7-associated genes across cancer lineages are RNA5SP455, RN7SL625P, and RNA5SP412. Each is linked with NOL7 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOL7-to-partner and partner-to-NOL7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOL7→partner) and Y-score (partner→NOL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP455 →	+0.332	+4.662	<.001	.003	3	2
UCEC	RN7SL625P →	+0.247	+2.676	.003	.007	3	1
UCEC	RNA5SP412 →	+0.926	+3.289	<.001	.001	3	1
UCEC	HNRNPCL3 →	+0.069	+2.871	<.001	.007	3	1
UCEC	PRAMEF12 →	+0.405	+2.577	.002	.009	3	1
UCEC	INSL4 →	+1.003	+3.753	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 86 associations by consensus.

Exploration

NOL7 survival (RNA) · tumor vs normal (RNA) · all NOL7 data types