Across TCGA patient cohorts, NOL7 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOL7-associated genes across cancer lineages are EGFR_pY1068, N-Ras, and CD31. Each is linked with NOL7 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOL7-to-partner and partner-to-NOL7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOL7→partner) and Y-score (partner→NOL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.315	-3.000	.030	.037	3	1
UCEC	N-Ras →	-0.168	-2.986	.014	.037	3	1
UCEC	CD31 →	-0.179	-3.000	.035	.037	3	1
UCEC	Ku80 →	+0.379	+3.013	.005	.019	2	1
UCEC	Axl →	-0.296	-2.963	.013	.037	2	1
UCEC	Tuberin →	+0.621	+2.817	<.001	.036	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

NOL7 survival (RNA) · tumor vs normal (RNA) · all NOL7 data types